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Advances in Optimization and Numerical Analysis Domänen und Squamous cell carcinoma of theIn January 1992, the Sixth Workshop on Optimization and Numerical Analysis was held in the heart of the Mixteco Zapoteca region, in the city of Oaxaca, Mexico, a beautiful and culturally rich site in ancient, colonial and modern Mexican civiliza tion. The Workshop was organized by the Numerical Analysis Department at the Institute of Research in Applied Mathematics of the National University of Mexico in collaboration with the Mathematical Sciences